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Phentermine HCI/Topiramate/Methylcobalamin Slow Release

Phentimate combines two of the most common medications for appetite suppressants approved by the FDA: phentermine and topiramate. Both are intended to be used as part of an overall weight loss plan, and together have increased weight loss efficacy. Phentimate is unique to Options Medical Weight Loss and was developed by Options’ Chief Medical Officer, Dr. Katrina Mattingly.

How it works

Phentermine is an adrenergic agonist that promote weight loss by mimicking the sympathetic nervous system, which is how your body responds to stress. It blocks the brain’s hunger signals by increasing the body’s release of catecholamines, which are chemicals made by the adrenal glands. These hormones are important in stress response and cause an increase in heart rate and a decrease in appetite.

Topiramate works by reducing bursts of electrical activity in your brain and restoring the normal balance of nerve activity. It is important to keep a homeostatic level of brain activity as hormones and neurons involved in the regulation of feeding are in the hypothalamus and brainstem. Therefore, topiramate, normalizes this regulation which leads to a decrease in appetite and feelings of fullness that last longer after eating.

How its prescribed

Phentimate is taken once a day in the morning. Typically, the medical provider will start you on a low dose and increase your dose after 14 days, if needed. You will have follow-up appointments with the medical provider or weight loss counselor to track your weight loss progress and discuss any medical questions or concerns. We recommend following an Options Diet Nutrition plan for best results while taking Phentimate.

You may be a candidate for Phentimate if you struggle to strictly adhere to a diet plan, have frequent hunger throughout the day, do not want to give up alcohol consumption, taking phentermine alone or as mono drug therapy, or if you’re looking for a long-term weight maintenance plan and can no longer continue phentermine.


Are Weight Loss Medications a Good Fit for Me?

Our team is qualified to guide you to the correct medication based on weight loss goals, health conditions, and medical history. With any medication there are side effects and contraindications, so not everyone can qualify for our medications. However, we have a team of Provider’s in our clinic who will review your medical history and perform a physical exam prior to dispensing the medication. Your safety and happiness is our mission! At your visit you will receive a thorough overview of our medications and leave feeling confident with your treatment regimen.


We all have to start somewhere. To get you on the right track to achieving your weight loss goals, we offer a free metabolic test and complimentary consultation to assess where you’re at and where you want to be. We’ll review your weight loss goals, medical history, current nutrition, and goal timeline. From there, we can customize a plan tailored to your individual needs, aspirations, and lifestyle. Our doctors will manage your prescriptions and our weight loss counselors will provide guidance on your diet and support you every step along the way. Submit the form above to get your free consultation.

The material on this website is for informational purposes only and is not a substitute for medical advice by a physician or treatment for any medical conditions. You should immediately seek professional medical care if you have any concern about your health. Options Medical Weight Loss™, Options Diet System™, Options HCG System™, “OPTIONS for every BODY™” are registered trademarks of Options Medical Weight Loss.